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RBMY1J and CBX2
Data Source:
BioGRID
(two hybrid)
RBMY1J
CBX2
Description
RNA binding motif protein Y-linked family 1 member J
chromobox 2
Image
No pdb structure
GO Annotations
Cellular Component
Cellular_component
Nuclear Speck
Euchromatin
Heterochromatin
Nucleus
Nucleoplasm
PcG Protein Complex
PRC1 Complex
Molecular Function
RNA Binding
Protein Binding
Identical Protein Binding
DNA Binding
Chromatin Binding
Protein Binding
Methylated Histone Binding
Biological Process
Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
Spermatogenesis
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Cell Differentiation
Development Of Primary Sexual Characteristics
Pathways
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Drugs
Diseases
46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS
Brain morphology (MOSTest) (
32665545
)
Interacting Genes
28 interacting genes:
APOBEC3C
CBX2
CNNM3
EPM2AIP1
HHEX
HNRNPK
LNX1
NPDC1
PCDHB14
PPP1R37
PRPF31
PRR3
RASD1
RBM3
RBMX
RBMY1A1
RBMY1E
RBMY1F
RNPS1
SNRPA
SPATC1L
TRA2B
U2AF2
YTHDC1
ZNF317
ZNF408
ZNF792
ZNF837
25 interacting genes:
BOLL
CYSRT1
DHX57
H3-4
KRTAP10-1
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP12-2
KRTAP12-3
KRTAP2-4
KRTAP4-12
KRTAP4-4
MDFI
MEOX2
PCGF2
PHC2
RBMY1A1
RBMY1F
RBMY1J
RBPMS2
RNF2
RYBP
TRIM55
TRIM63
Entrez ID
378951
84733
HPRD ID
15233
14397
Ensembl ID
ENSG00000226941
ENSG00000173894
Uniprot IDs
J3KQ82
Q15415
Q14781
PDB IDs
2D9U
3H91
5EPK
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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