CBX2 and RBMY1A1

Data Source:
BioGRID (two hybrid)

		CBX2	RBMY1A1
Description		chromobox 2	RNA binding motif protein Y-linked family 1 member A1
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GO Annotations	Cellular Component	Euchromatin Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Nuclear Speck
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Methylated Histone Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Cell Differentiation Development Of Primary Sexual Characteristics	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome
Pathways		Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases		46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS		Brain morphology (MOSTest) ( 32665545)
Interacting Genes		25 interacting genes: BOLL CYSRT1 DHX57 H3-4 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP2-4 KRTAP4-12 KRTAP4-4 MDFI MEOX2 PCGF2 PHC2 RBMY1A1 RBMY1F RBMY1J RBPMS2 RNF2 RYBP TRIM55 TRIM63	29 interacting genes: AEN APOBEC3C CBX2 CIRBP CLK3 DAAM2 DHX57 HBZ HNRNPK KHDRBS3 LMNTD2 LNX1 MYPOP PCDHB14 PRPF31 PRR3 RASD1 RBM3 RBMX RBMY1F RBMY1J SNRPA SRSF3 SRSF9 TERF1 TH TRA2B YTHDC1 ZNF317
Entrez ID		84733	5940
HPRD ID		14397	02450
Ensembl ID		ENSG00000173894	ENSG00000234414
Uniprot IDs		Q14781	P0DJD3
PDB IDs		2D9U 3H91 5EPK	2FY1
Enriched GO Terms of Interacting Partners?
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