AQP2 and INSIG2

  • Data Source:
  • BioGRID (two hybrid)

AQP2

INSIG2

Description aquaporin 2 insulin induced gene 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Allergic rhinitis ( 30013184)
  • Obsessive-compulsive disorder ( 22889921)
  • Apolipoprotein B levels ( 32203549)
  • Cholesterol, total ( 24097068)
  • Depression in response to interferon-based therapy in chronic hepatitis C ( 27723809)
  • Heel bone mineral density ( 30598549 28869591)
  • LDL cholesterol ( 24097068 30275531)
  • LDL cholesterol levels ( 32203549 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Lumbar spine bone mineral density ( 22504420)
  • Monobrow ( 27182965)
  • Mosquito bite size ( 28199695)
  • Total cholesterol levels ( 30275531)
Interacting Genes 60 interacting genes: ACTB BCAP31 C4orf3 CCDC167 CDIPT CERT1 CLCA4 CLDN7 CREB3 CREB3L1 CTSA CXCL16 EEF1A1 EFNA5 ELL2 ERG28 ERGIC3 ERMP1 FAM209A GPAA1 GPX8 IER3 IGFBP5 INSIG2 LEUTX LHFPL5 MRM1 MS4A13 MUC1 NDFIP2 OLFM4 OR10AG1 PANX1 PDZK1IP1 PLP2 PNLIPRP1 RTP2 SLC26A6 SLC30A2 SLC38A7 SLC5A2 SNAP47 SNX5 SPCS1 SSR3 STUB1 STX8 SUPT20H TM9SF2 TMEM109 TMEM218 TMEM230 TMEM236 TMEM60 TMEM86A TMEM97 TRARG1 UBE2J1 VAPB YIPF6 46 interacting genes: ABHD4 AQP2 AQP6 ATP6V0B BIK CD40 CD79A CPLX4 CREB3L1 CYBC1 EBP FAM209A GJA8 GOLM1 GPR152 GPR37L1 GPX8 HSD17B13 IFNGR2 KIR2DL3 LAPTM5 LHFPL5 LMNA MMGT1 MUC1 NEMP1 PRLR PSCA PSMA7 PSMB1 PSMC3 PSMC5 PVR RNF5 SCAP SCN3B SLC16A10 SREBF2 STIM1 TMEM14B TMEM237 TMEM45B TMEM52B TMX2 VCP VMA21
Entrez ID 359 51141
HPRD ID 00141 16361
Ensembl ID ENSG00000167580 ENSG00000125629
Uniprot IDs P41181 A0A024RAI2 B4DQ23 Q9Y5U4
PDB IDs 4NEF 4OJ2 6QF5 4J82
Enriched GO Terms of Interacting Partners?
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