IGBP1 and SHOX

Data Source:
BioGRID (two hybrid)

		IGBP1	SHOX
Description		immunoglobulin binding protein 1	short stature homeobox
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein Phosphatase Regulator Activity Protein Phosphatase 2A Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Signal Transduction Negative Regulation Of Stress-activated MAPK Cascade Response To Tumor Necrosis Factor Regulation Of Dephosphorylation B Cell Activation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Microtubule-based Movement Response To Interleukin-1	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Corpus callosum, agenesis of, with mental retardation, ocular coloboma and micrognathia	SHOX-related haploinsufficiency disorders, including: Isolated short stature; Langer syndrome; Leri-Weill syndrome
GWAS
Interacting Genes		12 interacting genes: APP HSPB1 LINC01257 MID1 MID2 PPP2CA PPP4C PPP6C PYGM REXO5 S100A13 SHOX	5 interacting genes: CSNK2A1 GLIS2 HEMK1 IGBP1 NKX2-5
Entrez ID		3476	6473
HPRD ID		02140	02430
Ensembl ID		ENSG00000089289	ENSG00000185960
Uniprot IDs		P78318	A0A024R385 O15266
PDB IDs		4IYP
Enriched GO Terms of Interacting Partners?
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