IGBP1 and PPP6C

Data Source:
HPRD (two hybrid)

		IGBP1	PPP6C
Description		immunoglobulin binding protein 1	protein phosphatase 6 catalytic subunit
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Golgi Membrane Mitochondrion Cytosol
	Molecular Function	Protein Binding Protein Phosphatase Regulator Activity Protein Phosphatase 2A Binding	Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Signal Transduction Negative Regulation Of Stress-activated MAPK Cascade Response To Tumor Necrosis Factor Regulation Of Dephosphorylation B Cell Activation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Microtubule-based Movement Response To Interleukin-1	G1/S Transition Of Mitotic Cell Cycle Protein Dephosphorylation Innate Immune Response COPII Vesicle Coating
Pathways			Telomere Extension By Telomerase COPII-mediated vesicle transport
Drugs
Diseases		Corpus callosum, agenesis of, with mental retardation, ocular coloboma and micrognathia
GWAS			Pulse pressure ( 27841878) Refractive error ( 32231278) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		12 interacting genes: APP HSPB1 LINC01257 MID1 MID2 PPP2CA PPP4C PPP6C PYGM REXO5 S100A13 SHOX	7 interacting genes: IGBP1 NFKBIE PRKDC TGFBR1 TIPRL VAC14 ZNRF2
Entrez ID		3476	5537
HPRD ID		02140	02141
Ensembl ID		ENSG00000089289	ENSG00000119414
Uniprot IDs		P78318	A0A024R861 O00743
PDB IDs		4IYP
Enriched GO Terms of Interacting Partners?
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