ZFP57 and YOD1

Data Source:
BioGRID (two hybrid)

		ZFP57	YOD1
Description		ZFP57 zinc finger protein	YOD1 deubiquitinase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Metal Ion Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Ubiquitin Protein Ligase Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression By Genetic Imprinting Regulation Of Transcription By RNA Polymerase II DNA Methylation Involved In Embryo Development	Macroautophagy Protein Deubiquitination Protein Phosphopantetheinylation Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Protein K29-linked Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Protein K27-linked Deubiquitination Protein K33-linked Deubiquitination
Pathways			Ovarian tumor domain proteases
Drugs
Diseases		Transient neonatal diabetes mellitus (TNDM)
GWAS		Albumin-globulin ratio ( 29403010) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Offspring birth weight ( 31043758) White matter integrity (mean diffusivity) ( 32358547)	Systolic blood pressure ( 28234671)
Interacting Genes		8 interacting genes: CIB3 DVL3 EMD KANK2 MKRN3 MLH1 POLR1C YOD1	30 interacting genes: BIRC3 DAZAP2 DDIT4L FAM168A INCA1 LMO2 MKRN1 NEDD4 NGRN PLEKHB2 PSMA7 RFC2 RIPK1 RNF216 SHARPIN SNCA SPART TP53BP2 TRAF6 TRIM54 TRIM55 TRIM63 TRIM8 UBC UBE3A UBXN6 USP15 USP21 VCP ZFP57
Entrez ID		346171	55432
HPRD ID		19560	10312
Ensembl ID		ENSG00000204644	ENSG00000180667
Uniprot IDs		A0A1U9X8V5 B7ZW61 Q9NU63	Q5VVQ6
PDB IDs			4BOQ 4BOS 4BOZ
Enriched GO Terms of Interacting Partners?
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