AQP8 and STX12

Data Source:
BioGRID (two hybrid)

		AQP8	STX12
Description		aquaporin 8	syntaxin 12
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Mitochondrial Membrane Apical Part Of Cell	Golgi Membrane Phagophore Assembly Site Nucleoplasm Golgi Apparatus Synaptic Vesicle Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane BLOC-1 Complex SNARE Complex Early Endosome Membrane Vesicle Intracellular Membrane-bounded Organelle Membrane Raft Phagocytic Vesicle Recycling Endosome Membrane Postsynaptic Recycling Endosome
	Molecular Function	Protein Binding Water Channel Activity	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Water Transport Transmembrane Transport Cellular Response To CAMP	Autophagosome Assembly Intracellular Protein Transport Vesicle Fusion Cholesterol Efflux Vesicle Docking Protein Stabilization
Pathways		Detoxification of Reactive Oxygen Species Passive transport by Aquaporins
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 27400856)
Interacting Genes		6 interacting genes: CYBC1 PLP2 PLPP6 SERP1 STX12 TMEM120B	43 interacting genes: AQP6 AQP8 BCL2L13 BLOC1S6 CD79A CISD2 DNAJC5 DTX2 EBP EEA1 EPB42 ERGIC3 FCER1G GORAB HOMER1 KASH5 LEPROTL1 LMNA MFSD6 MMGT1 NAPA NEMP1 NSG1 PDZK1IP1 PLPPR2 RIC3 SEC11C SLC10A6 SLC66A2 SNAP23 SNAP25 SNAP29 STX1A STX2 STX4 STXBP5L TIMMDC1 TLCD4 TMEM14B TMEM167B TMEM31 TMEM86B TMX2
Entrez ID		343	23673
HPRD ID		04778	06059
Ensembl ID		ENSG00000103375	ENSG00000117758
Uniprot IDs		O94778	Q86Y82
PDB IDs			2DNX
Enriched GO Terms of Interacting Partners?
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