STX12 and AQP8

Data Source:
BioGRID (two hybrid)

		STX12	AQP8
Description		syntaxin 12	aquaporin 8
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Phagophore Assembly Site Nucleoplasm Golgi Apparatus Synaptic Vesicle Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane BLOC-1 Complex SNARE Complex Early Endosome Membrane Vesicle Intracellular Membrane-bounded Organelle Membrane Raft Phagocytic Vesicle Recycling Endosome Membrane Postsynaptic Recycling Endosome	Plasma Membrane Integral Component Of Plasma Membrane Mitochondrial Membrane Apical Part Of Cell
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	Protein Binding Water Channel Activity
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Vesicle Fusion Cholesterol Efflux Vesicle Docking Protein Stabilization	Water Transport Transmembrane Transport Cellular Response To CAMP
Pathways			Detoxification of Reactive Oxygen Species Passive transport by Aquaporins
Drugs
Diseases
GWAS			Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 27400856)
Interacting Genes		43 interacting genes: AQP6 AQP8 BCL2L13 BLOC1S6 CD79A CISD2 DNAJC5 DTX2 EBP EEA1 EPB42 ERGIC3 FCER1G GORAB HOMER1 KASH5 LEPROTL1 LMNA MFSD6 MMGT1 NAPA NEMP1 NSG1 PDZK1IP1 PLPPR2 RIC3 SEC11C SLC10A6 SLC66A2 SNAP23 SNAP25 SNAP29 STX1A STX2 STX4 STXBP5L TIMMDC1 TLCD4 TMEM14B TMEM167B TMEM31 TMEM86B TMX2	6 interacting genes: CYBC1 PLP2 PLPP6 SERP1 STX12 TMEM120B
Entrez ID		23673	343
HPRD ID		06059	04778
Ensembl ID		ENSG00000117758	ENSG00000103375
Uniprot IDs		Q86Y82	O94778
PDB IDs		2DNX
Enriched GO Terms of Interacting Partners?
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