TLX3 and FAM168B

Data Source:
BioGRID (two hybrid)

		TLX3	FAM168B
Description		T cell leukemia homeobox 3	family with sequence similarity 168 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Plasma Membrane Integral Component Of Membrane Axon Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Neuron Migration Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Respiratory Gaseous Exchange By Respiratory System Negative Regulation Of Neuron Differentiation Animal Organ Development Neuron Fate Specification
Pathways
Drugs
Diseases		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Body size at age 10 ( 32376654)
Interacting Genes		106 interacting genes: ACY1 AKAP9 ANKRD10 ANKRD33 AOC1 APBB1IP ARMC5 ASB12 ATP6V0D1 B9D2 BPIFA1 C11orf1 C11orf45 C19orf54 C2orf42 CEACAM6 CRX CSNK2B CTNNA3 DENND4A EFEMP2 ERAS FAM166B FAM168B FCSK FNTB FOSB FOXH1 GGTLC2 GOLGA6L9 GTF2A1L H2BC11 HNRNPUL1 HOPX HSPB2 HSPB2-C11orf52 HYI IGFL2 ING4 INTS11 IRF9 ITIH6 KRT34 KRTAP11-1 KRTAP13-3 KRTAP19-1 KRTAP19-7 KRTAP3-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LASP1 LMO2 MAGED1 MEIS1 METTL27 MORN5 MSX2 NDUFAB1 NHLRC4 NICN1 OIP5 PLA2G10 PLAAT1 POU2AF1 POU6F2 PPP1CC PQBP1 PRR20A PRR20B PRR20C PRR20D PRR20E PSMB11 REL ROR2 RSKR SERPINE1 SLC15A2 SMU1 SNTA1 SP1 SPATA46 SPRYD7 STH SYNGAP1 TBX22 TCIRG1 TEKT5 TEX37 THTPA TLE1 TLE2 TMEM42 TOX2 TP53BP1 TRIM42 UFSP1 WDR83 YPEL3 ZBTB32 ZNF34 ZNF41 ZNF44	51 interacting genes: AGXT ARID5A BAG3 CAMK2A CCNK CSTF2 CSTF2T EGLN3 FAM168A FAM222B FOXH1 FOXI1 GLIS2 GPS2 HOXB9 HSF4 KRTAP26-1 LASP1 MED25 MSRB3 MYOZ3 NEDD9 OTX1 PATZ1 PITX1 POGZ POM121 PPP1R32 PRR35 RAMAC RBFOX2 RHOXF2 ROR2 SAMD7 SNRPB SNRPC SPAG8 TCF7L2 TENT5B TIAL1 TLE5 TLX3 UBAP2 VENTX VEZF1 VGLL3 VPS37C WDR25 YPEL3 ZC3H10 ZIC1
Entrez ID		30012	130074
HPRD ID		06868	17295
Ensembl ID		ENSG00000164438	ENSG00000152102
Uniprot IDs		O43711	A0A024QZ31 A1KXE4
PDB IDs
Enriched GO Terms of Interacting Partners?
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