GYPB and RHAG

Data Source:
HPRD (in vivo)

		GYPB	RHAG
Description		glycophorin B (MNS blood group)	Rh associated glycoprotein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Ammonium Transmembrane Transporter Activity Leak Channel Activity Ankyrin Binding Carbon Dioxide Transmembrane Transporter Activity
	Biological Process	Leukocyte Migration	Cellular Ion Homeostasis Carbon Dioxide Transport Ammonium Transport Bicarbonate Transport Carbon Dioxide Transmembrane Transport Ammonium Transmembrane Transport Inorganic Cation Transmembrane Transport
Pathways		Cell surface interactions at the vascular wall	Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide Rhesus glycoproteins mediate ammonium transport. Defective RHAG causes regulator type Rh-null hemolytic anemia (RHN)
Drugs
Diseases			Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Malaria ( 31844061) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Neutrophil count ( 32888494) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Red blood cell count ( 32888494) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Severe malaria ( 26416757) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 32888494)	Alcohol dependence ( 26365420) Mean corpuscular hemoglobin concentration ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		5 interacting genes: HSD17B13 REEP4 RHAG S1PR3 UBQLN1	11 interacting genes: ANK1 CD47 CREB3L3 ERGIC3 FAM209A GYPB ICAM4 LMNA SLC4A1 TEX29 UNC93A
Entrez ID		2994	6005
HPRD ID		00201	01582
Ensembl ID		ENSG00000250361	ENSG00000112077
Uniprot IDs		B8Q175 D6RBP2 P06028	Q02094 Q96E98
PDB IDs
Enriched GO Terms of Interacting Partners?
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