GYPB and S1PR3

Data Source:
BioGRID (two hybrid)

		GYPB	S1PR3
Description		glycophorin B (MNS blood group)	sphingosine-1-phosphate receptor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Integrin Binding Protein Binding Lipid Binding Sphingosine-1-phosphate Receptor Activity
	Biological Process	Leukocyte Migration	Sphingosine-1-phosphate Receptor Signaling Pathway Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Notch Signaling Pathway Positive Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis Regulation Of Metabolic Process Regulation Of Interleukin-1 Beta Production Negative Regulation Of Establishment Of Endothelial Barrier
Pathways		Cell surface interactions at the vascular wall	G alpha (i) signalling events Lysosphingolipid and LPA receptors Extra-nuclear estrogen signaling
Drugs			Fingolimod
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Malaria ( 31844061) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Neutrophil count ( 32888494) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Red blood cell count ( 32888494) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Severe malaria ( 26416757) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 32888494)	Cardiometabolic and hematological traits ( 27668658) Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Monocyte percentage of white cells ( 32888494 27863252) Response to statins (LDL cholesterol change) ( 22331829) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		5 interacting genes: HSD17B13 REEP4 RHAG S1PR3 UBQLN1	6 interacting genes: COMT GNA13 GNAI1 GNAQ GYPB HTR1A
Entrez ID		2994	1903
HPRD ID		00201	03572
Ensembl ID		ENSG00000250361	ENSG00000213694
Uniprot IDs		B8Q175 D6RBP2 P06028	Q99500
PDB IDs
Enriched GO Terms of Interacting Partners?
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