S1PR3 and GYPB

Data Source:
BioGRID (two hybrid)

		S1PR3	GYPB
Description		sphingosine-1-phosphate receptor 3	glycophorin B (MNS blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	G Protein-coupled Receptor Activity Integrin Binding Protein Binding Lipid Binding Sphingosine-1-phosphate Receptor Activity	Protein Binding
	Biological Process	Sphingosine-1-phosphate Receptor Signaling Pathway Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Notch Signaling Pathway Positive Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis Regulation Of Metabolic Process Regulation Of Interleukin-1 Beta Production Negative Regulation Of Establishment Of Endothelial Barrier	Leukocyte Migration
Pathways		G alpha (i) signalling events Lysosphingolipid and LPA receptors Extra-nuclear estrogen signaling	Cell surface interactions at the vascular wall
Drugs		Fingolimod
Diseases
GWAS		Cardiometabolic and hematological traits ( 27668658) Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Monocyte percentage of white cells ( 32888494 27863252) Response to statins (LDL cholesterol change) ( 22331829) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Malaria ( 31844061) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Neutrophil count ( 32888494) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Red blood cell count ( 32888494) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Severe malaria ( 26416757) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 32888494)
Interacting Genes		6 interacting genes: COMT GNA13 GNAI1 GNAQ GYPB HTR1A	5 interacting genes: HSD17B13 REEP4 RHAG S1PR3 UBQLN1
Entrez ID		1903	2994
HPRD ID		03572	00201
Ensembl ID		ENSG00000213694	ENSG00000250361
Uniprot IDs		Q99500	B8Q175 D6RBP2 P06028
PDB IDs
Enriched GO Terms of Interacting Partners?
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