GPR35 and APH1A

  • Data Source:
  • BioGRID (two hybrid)

GPR35

APH1A

Description G protein-coupled receptor 35 aph-1 homolog A, gamma-secretase subunit
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Ankylosing spondylitis ( 23749187)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 25489960)
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • Inflammatory bowel disease ( 28067908 23128233)
  • Monocyte count ( 27863252)
  • Monocyte percentage of white cells ( 32888494 27863252)
  • Pediatric autoimmune diseases ( 26301688)
  • Sclerosing cholangitis and ulcerative colitis (combined) ( 22821403)
  • Ulcerative colitis ( 28067908 21297633)
Interacting Genes 59 interacting genes: ABHD14A ADGRB1 AIG1 APH1A ATP1A1 ATP2C1 AUP1 B3GAT3 B4GALT2 BNIP1 CANX CD81 CH25H CMTM3 CRHR2 ERGIC3 FLRT1 FTH1 GHITM GJC2 GPR146 GPR161 HLA-A KCNJ4 KDELR1 LSS MCOLN1 MSMO1 NPC1 NSDHL OSTC PLD3 PLLP PLXDC1 PPP1R3F RTN3 RTN4 SCARB1 SDHD SELENOK SLC15A4 SLC2A1 SLC31A2 SLC37A1 SLC37A4 SLC45A4 SLC8A2 SLC9A7 SPART SYNGR2 SYT11 TMEM161A TMEM94 TSPAN7 VPS25 VTI1B YIF1B ZDHHC3 ZFAND1 36 interacting genes: ANKRD46 APOD ASGR1 ATF4 BHLHE40 CREB3 DRD2 FIS1 FXYD6 GLP1R GPATCH8 GPR35 HES1 HIVEP1 IGFBP5 KLF11 LAT MFSD6 MPP1 MRAP2 NCSTN PSEN1 PSEN2 PSENEN RBFOX2 SCAND1 SERP1 SLC38A7 SLC39A9 SMAGP THPO TLE1 TMED10 TMEM140 TMEM218 TRARG1
Entrez ID 2859 51107
HPRD ID 16003 06360
Ensembl ID ENSG00000178623 ENSG00000117362
Uniprot IDs A8K2J1 B2RA17 Q9HC97 B4DUG7 Q96BI3
PDB IDs 5A63 5FN2 5FN3 5FN4 5FN5 6IDF 6IYC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
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