SREK1IP1 and NME1

Data Source:
BioGRID (two hybrid)

		SREK1IP1	NME1
Description		SREK1 interacting protein 1	NME/NM23 nucleoside diphosphate kinase 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Mitochondrial Outer Membrane Centrosome Cytosol Intermediate Filament Membrane Ruffle Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding	Magnesium Ion Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Single-stranded DNA Binding RNA Binding Deoxyribonuclease Activity Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding GTP Binding Intermediate Filament Binding Enzyme Binding Identical Protein Binding Gamma-tubulin Binding Ribosomal Small Subunit Binding
	Biological Process	MRNA Processing RNA Splicing	Negative Regulation Of Myeloid Leukocyte Differentiation Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process DNA Metabolic Process Endocytosis Lactation Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Positive Regulation Of Neuron Projection Development Response To Amine Nucleobase-containing Small Molecule Interconversion Hippocampus Development Cell Differentiation Response To Testosterone Cellular Response To Drug Regulation Of Apoptotic Process Positive Regulation Of DNA Binding Positive Regulation Of Epithelial Cell Proliferation Response To CAMP Cellular Response To Glucose Stimulus Cellular Response To Fatty Acid
Pathways			Interconversion of nucleotide di- and triphosphates
Drugs			Zinc 2'-Deoxyguanosine-5'-Triphosphate Selenocysteine 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate Adenosine Phosphonoacetic Acid Stavudine triphosphate Thymidine-5'- Diphosphate 2'-Deoxyguanosine-5'-Diphosphate 2',3'-dideoxy-3'-fluoro-urididine-5'-diphosphate Guanosine-5'-Diphosphate 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate Zidovudine diphosphate Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		General cognitive ability ( 29844566)	Bipolar disorder ( 31043756) Conjunctival UV autofluorescence (CUVAF) ( 25590795) Metabolite levels ( 23823483)
Interacting Genes		28 interacting genes: AGPAT3 C4orf45 CCNL1 CT45A1 DDIT4L ELOA2 FGF10 GTF2H4 H2BC15 HPRT1 HSD17B14 LYAR MACROH2A1 NKAPD1 NKAPL NME1 PPCDC PRPF40A PRR13 RBM39 RNF151 RP9 RP9P RPL9 SDCBP SDCBP2 STAC3 THAP1	31 interacting genes: APEX1 AURKA CCND3 FBXO24 FXR2 GORASP2 ITGB1 KSR1 LNX1 MIF NIF3L1 NME2 NME3 NME4 NTAQ1 NUTF2 PID1 POLR1C PRUNE1 RAC1 RORA RORB RRAD SET SMARCD1 SOX30 SREK1IP1 TERF1 TIAM1 TNPO2 TNPO3
Entrez ID		285672	4830
HPRD ID		08210	01131
Ensembl ID		ENSG00000153006	ENSG00000239672
Uniprot IDs		Q8N9Q2	A0A384MTW7 P15531
PDB IDs			1JXV 1UCN 2HVD 2HVE 3L7U 4ENO 5UI4
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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