SEC14L4 and BMF

Data Source:
BioGRID (two hybrid)

		SEC14L4	BMF
Description		SEC14 like lipid binding 4	Bcl2 modifying factor
Image			No pdb structure
GO Annotations	Cellular Component		Acrosomal Vesicle Mitochondrial Outer Membrane Cytosol Plasma Membrane Myosin Complex
	Molecular Function	Protein Binding Lipid Binding	Protein Binding
	Biological Process		Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Autophagy Positive Regulation Of Protein-containing Complex Assembly Cellular Response To UV Positive Regulation Of Apoptotic Process Anoikis Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Activation of BMF and translocation to mitochondria
Drugs		Vitamin E
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) High light scatter reticulocyte percentage of red cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Chronic lymphocytic leukemia ( 28165464 26956414 24292274) Dehydroepiandrosterone sulphate levels ( 21533175) Endometrial cancer ( 30093612 27135401) Endometrial cancer (endometrioid histology) ( 30093612) Endometrial endometrioid carcinoma ( 27135401) Ewing sarcoma ( 22327514) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Triglyceride levels ( 32203549)
Interacting Genes		21 interacting genes: BMF CRX CTAG1A CTAG1B HAO2 INCA1 KRT31 KRT34 MEOX1 MEOX2 PAX5 PAX6 PLEKHF2 REL RHOU SERTAD1 TCF4 TEPSIN TRIM54 USHBP1 ZMYND12	26 interacting genes: AQP1 BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L2 BCL2L2-PABPN1 CTAG1A CTAG1B CXCL9 DYNLL1 DYNLL2 GPSM3 LCN2 MAPK8 MCL1 MGAT5B MYO5A NNMT RECK REL SEC14L4 SHC3 TCF12 TFIP11 TRIM54
Entrez ID		284904	90427
HPRD ID		15312	05881
Ensembl ID		ENSG00000133488	ENSG00000104081
Uniprot IDs		B2RMR2 B3KRP9 Q6ICM2 Q9UDX3	Q96LC9
PDB IDs		4TLG
Enriched GO Terms of Interacting Partners?
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