NHLRC4 and SPAG8

Data Source:
BioGRID (two hybrid)

		NHLRC4	SPAG8
Description		NHL repeat containing 4	sperm associated antigen 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Acrosomal Vesicle Nucleus Cytoplasm Spindle Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Molecular_function Protein Binding Microtubule Binding
	Biological Process	Protein K48-linked Ubiquitination	Cell Cycle Spermatogenesis Single Fertilization Biological_process Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin concentration ( 27863252)	Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		20 interacting genes: CERK DDIT4L DMRT3 DTX2 ENKD1 HSF4 IGFN1 KRTAP13-2 KRTAP15-1 KRTAP26-1 MGAT5B MYLIP OTX1 PATZ1 PITX1 POGZ POU4F3 PRKAB2 SPAG8 TLX3	87 interacting genes: ARMC5 B9D2 BATF2 C19orf54 CARM1 CCDC120 CCNC CDC23 CFP CSTF2 CSTF2T CTAG1A CTAG1B DMRT3 DOK3 DTX2 DYNLL2 EGFL7 FAM168B GIGYF1 GLYCTK GPSM3 HR INCA1 INTS11 JMJD4 KDM3B KLHL32 KRT34 KRTAP10-8 KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP26-1 KRTAP3-1 KRTAP6-2 KRTAP7-1 LASP1 MEOX1 METTL15 MGAT5B NEDD4L NHLRC4 NSD3 NUDT21 PATZ1 PEF1 PFDN5 PHF1 PITX1 PLA2G10 PRMT1 PRMT2 PRMT5 PRR35 RAN RBP3 RIPK4 RNF125 RUSC1 SERGEF SMUG1 SMYD1 SNRPB SNRPC SYNGAP1 TEKT3 TEKT5 TENT5B TRIB3 TRIM42 TSC1 TTC23 UBAP2 UBQLN1 UBQLN4 USP2 VPS37C YPEL3 ZBTB32 ZIC1 ZNF34 ZNF581
Entrez ID		283948	26206
HPRD ID		11681	12039
Ensembl ID		ENSG00000257108	ENSG00000137098
Uniprot IDs		P0CG21	A0A140VJV0 Q99932
PDB IDs
Enriched GO Terms of Interacting Partners?
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