INO80E and PHF19

Data Source:
BioGRID (two hybrid)

		INO80E	PHF19
Description		INO80 complex subunit E	PHD finger protein 19
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Ino80 Complex	Nucleus Nucleoplasm ESC/E(Z) Complex
	Molecular Function	Protein Binding	DNA Binding Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	DNA Repair DNA Recombination Chromatin Remodeling Protein Deubiquitination	Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Histone H3-K27 Methylation
Pathways		UCH proteinases DNA Damage Recognition in GG-NER	PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 25673413) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Schizophrenia ( 28991256 25056061 29483656)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Birth weight ( 31043758 27680694) Corneal astigmatism ( 29422769) High density lipoprotein cholesterol levels ( 29403010) Prostate-specific antigen levels ( 28139693) Pulse pressure ( 28135244 27618448) Refractive error ( 32231278)
Interacting Genes		22 interacting genes: APPL1 CDC23 CRK FAM124A FAM161A GEM IKBKG KPNA2 LNX1 MAB21L3 MCRS1 MORN4 NHLH1 PHF19 PICK1 PIN1 PRKAA1 PSMA1 SDCBP TBRG1 TLE5 TNFAIP8	21 interacting genes: BAG4 CSNK2A1 DVL3 H3C1 HOMEZ HOXB5 INO80E KDM1A LZTS2 PICK1 POTEB3 RCOR3 SNIP1 SUV39H1 SUV39H2 THAP1 THAP7 TSPYL2 YTHDC1 ZNF837 ZRANB1
Entrez ID		283899	26147
HPRD ID		08816	17846
Ensembl ID		ENSG00000169592	ENSG00000119403
Uniprot IDs		J3KNE2 Q8NBZ0	A0A087X169 B7Z887 B7Z8H3 F5H8K3 Q5T6S3
PDB IDs			2E5Q 4BD3 6NQ3 6WAU
Enriched GO Terms of Interacting Partners?
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