PHF19 and HOMEZ

Data Source:
BioGRID (two hybrid)

		PHF19	HOMEZ
Description		PHD finger protein 19	homeobox and leucine zipper encoding
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GO Annotations	Cellular Component	Nucleus Nucleoplasm ESC/E(Z) Complex	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Histone H3-K27 Methylation	Regulation Of Transcription By RNA Polymerase II
Pathways		PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Birth weight ( 31043758 27680694) Corneal astigmatism ( 29422769) High density lipoprotein cholesterol levels ( 29403010) Prostate-specific antigen levels ( 28139693) Pulse pressure ( 28135244 27618448) Refractive error ( 32231278)	Height ( 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean platelet volume ( 32888494) Pulse pressure ( 27841878) Reticulocyte count ( 32888494) Systolic blood pressure ( 27841878)
Interacting Genes		21 interacting genes: BAG4 CSNK2A1 DVL3 H3C1 HOMEZ HOXB5 INO80E KDM1A LZTS2 PICK1 POTEB3 RCOR3 SNIP1 SUV39H1 SUV39H2 THAP1 THAP7 TSPYL2 YTHDC1 ZNF837 ZRANB1	114 interacting genes: ACTR10 AEN ANKRD11 ANKRD2 ARHGAP9 ASB6 AXIN1 BIVM BYSL C2orf42 CBX8 CCDC13 CCDC187 CCHCR1 CCNK CDC7 CENPS CENPS-CORT CFAP206 CTNNA3 DEF6 DGCR6 DHX16 DNTTIP1 EBF1 EIF4E2 ELOA ENKD1 FAM90A1 FARS2 GAS8 GFAP GPANK1 GRB2 HOXC8 HSF2BP IL16 INO80B JAKMIP2 KIFC3 KPNA2 LENG1 LGALS4 LMO1 LMO3 LNX1 LRRC7 LSM4 MAD2L1BP MAFG MAPK1 MED18 MORF4L2 MOS MRPL11 NCK1 NCK2 NEIL2 NEK6 NXF1 OSGIN1 PARVG PHF1 PHF19 PIBF1 PIN1 PLEKHA7 POLDIP3 PRKAA1 PRKAA2 PRPF18 PSMA1 RASL10A RBM39 RNF8 RPGR RPL9 RPP25 RPS25 SCNM1 SDCBP SEC23A SH3RF2 SMARCB1 SMARCD1 SMYD1 SNRPB2 SUMO2 SUMO3 TARS2 TBC1D30 TCEA2 TCEANC TEAD4 TLE5 TRAF4 TSGA10IP TXK USF1 VEZF1 VPS9D1 ZBTB25 ZBTB7A ZMYND19 ZNF165 ZNF250 ZNF280C ZNF35 ZNF417 ZNF580 ZNF629 ZNF688 ZNF76 ZSCAN5B
Entrez ID		26147	57594
HPRD ID		17846	12167
Ensembl ID		ENSG00000119403	ENSG00000215271
Uniprot IDs		A0A087X169 B7Z887 B7Z8H3 F5H8K3 Q5T6S3	Q8IX15
PDB IDs		2E5Q 4BD3 6NQ3 6WAU	2ECC 2YS9
Enriched GO Terms of Interacting Partners?
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