INO80E and NHLH1

Data Source:
BioGRID (two hybrid)

		INO80E	NHLH1
Description		INO80 complex subunit E	nescient helix-loop-helix 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Ino80 Complex	Chromatin Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	DNA Repair DNA Recombination Chromatin Remodeling Protein Deubiquitination	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 25673413) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		22 interacting genes: APPL1 CDC23 CRK FAM124A FAM161A GEM IKBKG KPNA2 LNX1 MAB21L3 MCRS1 MORN4 NHLH1 PHF19 PICK1 PIN1 PRKAA1 PSMA1 SDCBP TBRG1 TLE5 TNFAIP8	11 interacting genes: CCT7 CENPP CSRP3 HIVEP1 INO80E LMO1 LMO2 LMO4 PIM1 PSME2 TCF3
Entrez ID		283899	4807
HPRD ID		08816	01212
Ensembl ID		ENSG00000169592	ENSG00000171786
Uniprot IDs		J3KNE2 Q8NBZ0	Q02575 Q5T203
PDB IDs
Enriched GO Terms of Interacting Partners?
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