RND1 and UBXN11

Data Source:
BioGRID (pull down, affinity chromatography technology, biochemical)
HPRD (in vitro, two hybrid, in vivo)

		RND1	UBXN11
Description		Rho family GTPase 1	UBX domain protein 11
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Adherens Junction Cell Cortex Actin Cytoskeleton Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle	Cytoplasm Cytoskeleton
	Molecular Function	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding	Protein Binding Ubiquitin Binding
	Biological Process	Actin Filament Organization Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Neuron Remodeling Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Monocyte percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Platelet count ( 32888494)
Interacting Genes		23 interacting genes: ARFIP2 ARHGAP5 CCNI COPS2 CREB3L2 EEF1A1 FRS2 FRS3 GPX8 GRB7 ID3 MYH7 MYOM3 MYZAP NEDD1 PAIP1 PDE6D PLXNA1 PLXNB1 PLXNB2 RAI14 UBXN11 ZNF212	34 interacting genes: C14orf119 CFAP206 EIF4E EIF4E2 ENKD1 HGS IL16 LENG1 NEK6 PPM1K PRKAA1 PRKAB2 PRPF18 PRPF31 PRR35 PSMA1 RHOBTB3 RND1 RND2 RND3 RNF213 SCNM1 SH2D4A SNRPB TCEANC TLE5 TRAF2 TTC23 USHBP1 VCP VPS9D1 WDR25 ZFYVE9 ZGPAT
Entrez ID		27289	91544
HPRD ID		12357	10245
Ensembl ID		ENSG00000172602	ENSG00000158062
Uniprot IDs		Q92730	Q5T124
PDB IDs		2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?
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