RND1 and NEDD1

Data Source:
BioGRID (two hybrid)

		RND1	NEDD1
Description		Rho family GTPase 1	NEDD1 gamma-tubulin ring complex targeting factor
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Adherens Junction Cell Cortex Actin Cytoskeleton Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle	Pericentriolar Material Spindle Pole Nucleoplasm Centrosome Centriole Cytosol Plasma Membrane Ciliary Basal Body Apical Part Of Cell
	Molecular Function	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding	Protein Binding
	Biological Process	Actin Filament Organization Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Neuron Remodeling Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Division Protein Localization To Centrosome Ciliary Basal Body-plasma Membrane Docking
Pathways		SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Adventurousness ( 30643258) Autism ( 24189344) Breast size ( 22747683) Frontotemporal dementia ( 29724592) Frontotemporal dementia with GRN mutation ( 29724592) Manganese levels ( 26025379)
Interacting Genes		23 interacting genes: ARFIP2 ARHGAP5 CCNI COPS2 CREB3L2 EEF1A1 FRS2 FRS3 GPX8 GRB7 ID3 MYH7 MYOM3 MYZAP NEDD1 PAIP1 PDE6D PLXNA1 PLXNB1 PLXNB2 RAI14 UBXN11 ZNF212	3 interacting genes: EP300 FBLN1 RND1
Entrez ID		27289	121441
HPRD ID		12357	02655
Ensembl ID		ENSG00000172602	ENSG00000139350
Uniprot IDs		Q92730	A0A024RBE5 A8K1Z3 Q8NHV4
PDB IDs		2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?
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