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RND1

Description Rho family GTPase 1
Image
GO Annotations Cellular Component
  • Cytosol
  • Cytoskeleton
  • Plasma Membrane
  • Adherens Junction
  • Cell Cortex
  • Actin Cytoskeleton
  • Cytoplasmic Vesicle
  • Cell Projection
  • Intracellular Membrane-bounded Organelle
Molecular Function
  • GTPase Activity
  • Signaling Receptor Binding
  • Protein Binding
  • GTP Binding
  • Protein Kinase Binding
Biological Process
  • Actin Filament Organization
  • Negative Regulation Of Cell Adhesion
  • Establishment Or Maintenance Of Cell Polarity
  • Small GTPase Mediated Signal Transduction
  • Regulation Of Cell Shape
  • Neuron Remodeling
  • Cell Migration
  • Cortical Cytoskeleton Organization
  • Regulation Of Actin Cytoskeleton Organization
Pathways
  • SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
  • Sema4D mediated inhibition of cell attachment and migration
  • Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS
  • Bipolar disorder ( 21926972)
Novel Interacting Genes 2 novel interacting genes: KRT6A SHMT2
Interacting Genes 23 interacting genes: ARFIP2 ARHGAP5 CCNI COPS2 CREB3L2 EEF1A1 FRS2 FRS3 GPX8 GRB7 ID3 MYH7 MYOM3 MYZAP NEDD1 PAIP1 PDE6D PLXNA1 PLXNB1 PLXNB2 RAI14 UBXN11 ZNF212
Entrez ID 27289
HPRD ID 12357
Ensembl ID ENSG00000172602
Uniprot IDs Q92730
PDB IDs 2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025