TUBG2 and RNF19A

Data Source:
HPRD (in vivo)

		TUBG2	RNF19A
Description		tubulin gamma 2	ring finger protein 19A, RBR E3 ubiquitin protein ligase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Spindle Cytosol Microtubule Spindle Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton	Ubiquitin Ligase Complex Cytoplasm Centrosome Cytosol Integral Component Of Membrane Hippocampal Mossy Fiber To CA3 Synapse Postsynapse Glutamatergic Synapse
	Molecular Function	GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton GTP Binding	Protein Binding Transcription Factor Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Mitotic Sister Chromatid Segregation Meiotic Spindle Organization Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Mitotic Spindle Organization Cytoplasmic Microtubule Organization	Protein Polyubiquitination Microtubule Cytoskeleton Organization Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Tea consumption ( 31046077)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Atrioventricular conduction ( 21041692) Recurrent major depressive disorder ( 29317602)
Interacting Genes		3 interacting genes: PXN RNF19A TUBGCP3	17 interacting genes: C11orf58 CASR ILK MAP3K20 MAP3K7 NUDT21 RPS6KA5 SNCAIP SOD1 SUFU TUBG1 TUBG2 UBE2D2 UBE2E2 UBE2L3 UBE2L6 VCP
Entrez ID		27175	25897
HPRD ID		05778	06176
Ensembl ID		ENSG00000037042	ENSG00000034677
Uniprot IDs		A0A1B4Z394 Q9NRH3	Q9NV58
PDB IDs
Enriched GO Terms of Interacting Partners?
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