RNF19A and TUBG2

Data Source:
HPRD (in vivo)

		RNF19A	TUBG2
Description		ring finger protein 19A, RBR E3 ubiquitin protein ligase	tubulin gamma 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Centrosome Cytosol Integral Component Of Membrane Hippocampal Mossy Fiber To CA3 Synapse Postsynapse Glutamatergic Synapse	Pericentriolar Material Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Spindle Cytosol Microtubule Spindle Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton
	Molecular Function	Protein Binding Transcription Factor Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton GTP Binding
	Biological Process	Protein Polyubiquitination Microtubule Cytoskeleton Organization Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission	Mitotic Sister Chromatid Segregation Meiotic Spindle Organization Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Mitotic Spindle Organization Cytoplasmic Microtubule Organization
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Atrioventricular conduction ( 21041692) Recurrent major depressive disorder ( 29317602)	Tea consumption ( 31046077)
Interacting Genes		17 interacting genes: C11orf58 CASR ILK MAP3K20 MAP3K7 NUDT21 RPS6KA5 SNCAIP SOD1 SUFU TUBG1 TUBG2 UBE2D2 UBE2E2 UBE2L3 UBE2L6 VCP	3 interacting genes: PXN RNF19A TUBGCP3
Entrez ID		25897	27175
HPRD ID		06176	05778
Ensembl ID		ENSG00000034677	ENSG00000037042
Uniprot IDs		Q9NV58	A0A1B4Z394 Q9NRH3
PDB IDs
Enriched GO Terms of Interacting Partners?
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