LYPD3 and ATP1A3

Data Source:
HPRD (in vitro)

		LYPD3	ATP1A3
Description		LY6/PLAUR domain containing 3	ATPase Na+/K+ transporting subunit alpha 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Anchored Component Of Plasma Membrane	Photoreceptor Inner Segment Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Sodium:potassium-exchanging ATPase Complex Membrane Integral Component Of Membrane Axon Organelle Membrane Neuronal Cell Body Membrane Neuronal Cell Body Synapse Photoreceptor Inner Segment Membrane Neuron To Neuron Synapse Extracellular Vesicle
	Molecular Function	Laminin Binding	Amyloid-beta Binding P-type Sodium:potassium-exchanging ATPase Activity Protein Binding ATP Binding Metal Ion Binding Chaperone Binding Ion Antiporter Activity Involved In Regulation Of Presynaptic Membrane Potential Steroid Hormone Binding
	Biological Process	Cell-matrix Adhesion	Cellular Sodium Ion Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Regulation Of Resting Membrane Potential Cellular Response To Steroid Hormone Stimulus Cell Communication By Electrical Coupling Involved In Cardiac Conduction Proton Transmembrane Transport Response To Glycoside Regulation Of Cardiac Conduction Cellular Response To Amyloid-beta Neuron Projection Maintenance Potassium Ion Import Across Plasma Membrane
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs			Ouabain
Diseases			Primary torsion dystonia (PTD)
GWAS		Cotinine glucuronidation ( 25293881)	Brain morphology (MOSTest) ( 32665545) Meat-related diet ( 32066663)
Interacting Genes		17 interacting genes: AGR2 AGR3 AURKA BAG4 BRMS1 CASP8 CHEK2 CTRB1 ERBB2 IGF1R LSP1 PALB2 PPM1D PTPRJ RB1CC1 SMAD4 STK11	2 interacting genes: ATXN1 CASP8
Entrez ID		27076	478
HPRD ID		10783	01666
Ensembl ID		ENSG00000124466	ENSG00000105409
Uniprot IDs		B2RBR3 O95274	P13637 Q53ES0
PDB IDs		6IOM 6ION
Enriched GO Terms of Interacting Partners?
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