VPS41 and AP3D1

Data Source:
HPRD (in vitro, in vivo)

		VPS41	AP3D1
Description		VPS41 subunit of HOPS complex	adaptor related protein complex 3 subunit delta 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Microtubule Cytoskeleton AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane Clathrin Complex	Golgi Membrane Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane AP-3 Adaptor Complex Terminal Bouton Postsynapse Presynaptic Endosome Glutamatergic Synapse Axon Cytoplasm
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Protein Self-association Metal Ion Binding	Protein Binding
	Biological Process	Protein Targeting To Vacuole Endosome To Lysosome Transport Cellular Response To Starvation Macroautophagy Endosomal Vesicle Fusion Regulated Exocytosis Late Endosome To Lysosome Transport	Protein Targeting To Vacuole Intracellular Protein Transport Golgi To Vacuole Transport Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Transcription By RNA Polymerase II Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome
Pathways
Drugs
Diseases
GWAS		Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 19734545)	Height ( 28552196 31562340) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Myocardial infarction ( 24916648) Pulse pressure ( 30578418) Red blood cell count ( 32888494 27863252) Systolic blood pressure ( 30578418)
Interacting Genes		12 interacting genes: AKTIP AP3D1 APP ARL8B HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP UBE2U ZNF512B	12 interacting genes: AP3B1 AP3S1 AP3S2 ARF1 ARF6 CCN2 CDC42 DUX4 RUFY1 SLC30A3 VAMP7 VPS41
Entrez ID		27072	8943
HPRD ID		10402	06260
Ensembl ID		ENSG00000006715	ENSG00000065000
Uniprot IDs		P49754	O14617
PDB IDs			4AFI
Enriched GO Terms of Interacting Partners?
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