VPS41 and HOOK1

Data Source:
HPRD (in vivo)

		VPS41	HOOK1
Description		VPS41 subunit of HOPS complex	hook microtubule tethering protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Microtubule Cytoskeleton AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane Clathrin Complex	Cytoplasm Centrosome Cytosol Microtubule HOPS Complex FHF Complex
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Protein Self-association Metal Ion Binding	Actin Binding Protein Binding Microtubule Binding Identical Protein Binding Dynein Light Intermediate Chain Binding
	Biological Process	Protein Targeting To Vacuole Endosome To Lysosome Transport Cellular Response To Starvation Macroautophagy Endosomal Vesicle Fusion Regulated Exocytosis Late Endosome To Lysosome Transport	Golgi Organization Endosome Organization Lysosome Organization Multicellular Organism Development Endosome To Lysosome Transport Protein Transport Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport Manchette Assembly
Pathways
Drugs
Diseases
GWAS		Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 19734545)	Alcoholic chronic pancreatitis ( 28754779) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		12 interacting genes: AKTIP AP3D1 APP ARL8B HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP UBE2U ZNF512B	30 interacting genes: AKTIP ANK3 ANKRD23 CDC5L CDK4 CWF19L2 FAM161A FHIP1B HOOK2 HOOK3 LMO2 MEOX2 PIAS2 SYCE1 TBC1D7 TFIP11 USP2 UTP14C VPS16 VPS18 VPS39 VPS41 ZBTB47 ZNF250 ZNF35 ZNF572 ZNF655 ZNF764 ZNF785 ZNF80
Entrez ID		27072	51361
HPRD ID		10402	07428
Ensembl ID		ENSG00000006715	ENSG00000134709
Uniprot IDs		P49754	Q9UJC3
PDB IDs
Enriched GO Terms of Interacting Partners?
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