VPS41 and HOOK3

Data Source:
HPRD (in vivo)

		VPS41	HOOK3
Description		VPS41 subunit of HOPS complex	hook microtubule tethering protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Microtubule Cytoskeleton AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane Clathrin Complex	Pericentriolar Material Cytoplasm Cis-Golgi Network Centrosome Cytosol Microtubule HOPS Complex Centriolar Satellite FHF Complex
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Protein Self-association Metal Ion Binding	Protein Binding Microtubule Binding Dynactin Binding Identical Protein Binding Dynein Light Chain Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Protein Targeting To Vacuole Endosome To Lysosome Transport Cellular Response To Starvation Macroautophagy Endosomal Vesicle Fusion Regulated Exocytosis Late Endosome To Lysosome Transport	Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Interkinetic Nuclear Migration Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Microtubule Anchoring At Centrosome Early Endosome To Late Endosome Transport Negative Regulation Of Neurogenesis Golgi Localization Protein Localization To Centrosome Neuronal Stem Cell Population Maintenance
Pathways
Drugs
Diseases
GWAS		Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 19734545)	Zinc levels ( 26025379)
Interacting Genes		12 interacting genes: AKTIP AP3D1 APP ARL8B HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP UBE2U ZNF512B	11 interacting genes: AKTIP CTIF HOOK1 HOOK2 KRT13 KRT27 MAPT MEOX2 PNMA5 VPS16 VPS41
Entrez ID		27072	84376
HPRD ID		10402	09699
Ensembl ID		ENSG00000006715	ENSG00000168172
Uniprot IDs		P49754	Q86VS8
PDB IDs			5J8E 6B9H
Enriched GO Terms of Interacting Partners?
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