GJB1 and SERTM1

Data Source:
BioGRID (two hybrid)

		GJB1	SERTM1
Description		gap junction protein beta 1	serine rich and transmembrane domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Connexin Complex Integral Component Of Membrane	Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Gap Junction Channel Activity Protein Binding	Protein Binding
	Biological Process	Cell-cell Signaling Nervous System Development Gap Junction Assembly Transmembrane Transport
Pathways		Oligomerization of connexins into connexons Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS			Cocaine dependence ( 31212010) Nickel levels ( 26025379) Urinary albumin excretion ( 32277301)
Interacting Genes		57 interacting genes: APOL3 APP BMP10 C1GALT1 C2CD2L C3orf52 CALM1 CD37 CD79A CDIPT CLEC7A CMTM3 CMTM5 CNST COMT CTXN3 CXCL9 EFNA5 EGFR EMP3 EPHA1 GJB2 GLP1R GPR25 IER3IP1 ITGAM LAT LHFPL2 MAL MAL2 MFF MS4A13 MST1R NDUFB11 NIPAL4 PRKACA PRKCA PTPN2 PTPN9 RTP2 SCD SERTM1 SLC12A7 SRC STX8 TEX264 TF TM4SF4 TMEM120B TMEM14C TMEM19 TMEM218 TMEM98 UPK1B VEGFA VKORC1 YIPF6	14 interacting genes: APP CD53 CLDN7 EMP1 GJB1 GPR42 GPX8 KCNJ6 LHFPL5 LRRC4C MS4A4A MTIF3 SPACA1 TMEM19
Entrez ID		2705	400120
HPRD ID		02367	14219
Ensembl ID		ENSG00000169562	ENSG00000180440
Uniprot IDs		A0A654ICJ7 P08034	A2A2V5
PDB IDs		1TXH 5KK9
Enriched GO Terms of Interacting Partners?
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