BEX3 and ING4

Data Source:
BioGRID (two hybrid)

		BEX3	ING4
Description		brain expressed X-linked 3	inhibitor of growth family member 4
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytosol Intermediate Filament Cytoskeleton MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Signaling Receptor Binding Nerve Growth Factor Receptor Binding Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Identical Protein Binding Metal Ion Binding	Transcription Coactivator Activity Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Signal Transduction Multicellular Organism Development Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process	DNA Replication Protein Acetylation Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth
Pathways		NADE modulates death signalling	HATs acetylate histones
Drugs
Diseases
GWAS
Interacting Genes		41 interacting genes: AIMP2 BFSP2 CACYBP CBY2 CCDC116 CCDC85B CTNNBL1 DIABLO EMILIN1 ENKD1 FSD2 GOLGA8EP GOLGA8F ING4 ING5 KRT34 MCCD1 MDFI MIF MNAT1 NECAB2 NGFR NTRK3 PTPN13 S100A1 S100Z SIVA1 SMARCD1 SMPD1 TACC3 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TSNAX USHBP1 VTA1 YWHAE ZNF417	21 interacting genes: BEX3 CDC34 EGLN1 EP300 GRIPAP1 H3-4 H3C1 HNRNPD HOXB9 JADE2 KAT7 MAPK8IP2 MSX1 MYC NAV2 RELA SUV39H1 TLX3 TP53 TRIM55 TRIM63
Entrez ID		27018	51147
HPRD ID		02291	09774
Ensembl ID		ENSG00000166681	ENSG00000111653
Uniprot IDs		Q00994	Q9UNL4
PDB IDs		1SA6	2K1J 2M1R 2PNX 2VNF 4AFL
Enriched GO Terms of Interacting Partners?
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