ING4 and JADE2

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid)

		ING4	JADE2
Description		inhibitor of growth family member 4	jade family PHD finger 2
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytosol Intermediate Filament Cytoskeleton MOZ/MORF Histone Acetyltransferase Complex	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity Protein Binding Methylated Histone Binding Metal Ion Binding	Protein Binding Transferase Activity Metal Ion Binding
	Biological Process	DNA Replication Protein Acetylation Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation
Pathways		HATs acetylate histones	HATs acetylate histones
Drugs
Diseases
GWAS			Adult body size ( 32376654) Age at first birth ( 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)
Interacting Genes		21 interacting genes: BEX3 CDC34 EGLN1 EP300 GRIPAP1 H3-4 H3C1 HNRNPD HOXB9 JADE2 KAT7 MAPK8IP2 MSX1 MYC NAV2 RELA SUV39H1 TLX3 TP53 TRIM55 TRIM63	16 interacting genes: CBX8 CDCA7L CSNK2A1 FBXO7 GAS2L2 GORASP2 H3-4 ING4 ING5 MEAF6 PACSIN1 SASH1 ZBTB3 ZBTB5 ZNF417 ZNF496
Entrez ID		51147	23338
HPRD ID		09774	15124
Ensembl ID		ENSG00000111653	ENSG00000043143
Uniprot IDs		Q9UNL4	A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1
PDB IDs		2K1J 2M1R 2PNX 2VNF 4AFL
Enriched GO Terms of Interacting Partners?
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