CYFIP2 and DNMBP

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		CYFIP2	DNMBP
Description		cytoplasmic FMR1 interacting protein 2	dynamin binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane SCAR Complex Neuron Projection Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome	Golgi Apparatus Golgi Stack Cytoskeleton Cell-cell Junction Synapse Presynapse
	Molecular Function	RNA 7-methylguanosine Cap Binding Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Cell Morphogenesis Apoptotic Process Regulation Of Actin Filament Polymerization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Proteolysis Vascular Endothelial Growth Factor Receptor Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity Cell-cell Adhesion	Aging Regulation Of Cell Shape Intracellular Signal Transduction Regulation Of Catalytic Activity
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Asthma ( 31959851 32296059) Daytime sleep phenotypes ( 27126917) FEV1 ( 30804560) Gamma glutamyl transferase levels ( 29403010) Lung function (FEV1/FVC) ( 28166213 30804560) Peak expiratory flow ( 30804560) T-Cell Immunoglobulin and Mucin domain 1 levels ( 32460577)	Stent thrombosis in response to clopidogrel treatment ( 32472697)
Interacting Genes		22 interacting genes: ABI1 ABI3 APBB1 BIRC3 BRK1 DNMBP FMR1 FXR1 FXR2 GAS7 MTDH NCK1 NCKAP1 OXTR PLG PRPF40A SMAD4 TCERG1 WASF1 WASF2 YWHAG ZC3H12A	20 interacting genes: ACTA1 ARHGAP17 BUB1B CDC42 CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAC1 RAPH1 VASP WASF1 WASL WIPF2
Entrez ID		26999	23268
HPRD ID		07556	10918
Ensembl ID		ENSG00000055163	ENSG00000107554
Uniprot IDs		B7Z8N7 E7EVJ5 Q96F07	A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7
PDB IDs			1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM
Enriched GO Terms of Interacting Partners?
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