DNMBP and EVL

Data Source:
HPRD (in vitro, two hybrid)

		DNMBP	EVL
Description		dynamin binding protein	Enah/Vasp-like
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Golgi Stack Cytoskeleton Cell-cell Junction Synapse Presynapse	Cytoplasm Cytosol Cytoskeleton Focal Adhesion Membrane Lamellipodium
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding
	Biological Process	Aging Regulation Of Cell Shape Intracellular Signal Transduction Regulation Of Catalytic Activity	Actin Filament Organization Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Actin Polymerization Or Depolymerization Animal Organ Morphogenesis Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Polymerization Actin Nucleation Protein Homotetramerization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly
Pathways			Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Stent thrombosis in response to clopidogrel treatment ( 32472697)	Blood protein levels ( 30072576) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 25663218)
Interacting Genes		20 interacting genes: ACTA1 ARHGAP17 BUB1B CDC42 CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAC1 RAPH1 VASP WASF1 WASL WIPF2	33 interacting genes: ABI1 ABI3 ABL1 APBB1 APBB1IP CRKL DNMBP ENAH FYB1 FYN HCK HTT LYN PFN2 POT1 PRPF40A RAD51 SEMA6A SH3RF1 SPTA1 SPTAN1 SRC TCERG1 TERF1 TES TRIM9 VASP WAS WASL XIRP1 ZDHHC17 ZNF655 ZYX
Entrez ID		23268	51466
HPRD ID		10918	10942
Ensembl ID		ENSG00000107554	ENSG00000196405
Uniprot IDs		A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7	A0A024R6K5 Q9UI08
PDB IDs		1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM
Enriched GO Terms of Interacting Partners?
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