DNMBP and BUB1B

Data Source:
BioGRID (two hybrid)

		DNMBP	BUB1B
Description		dynamin binding protein	BUB1 mitotic checkpoint serine/threonine kinase B
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GO Annotations	Cellular Component	Golgi Apparatus Golgi Stack Cytoskeleton Cell-cell Junction Synapse Presynapse	Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome Kinetochore Condensed Chromosome Outer Kinetochore Anaphase-promoting Complex Cytoplasm Microtubule Organizing Center Spindle Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Aging Regulation Of Cell Shape Intracellular Signal Transduction Regulation Of Catalytic Activity	Mitotic Cell Cycle Protein Phosphorylation Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Metaphase/anaphase Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Anaphase-promoting Complex-dependent Catabolic Process Cell Division Meiotic Sister Chromatid Cohesion, Centromeric Protein Localization To Chromosome, Centromeric Region Regulation Of Mitotic Cell Cycle Phase Transition
Pathways			Inactivation of APC/C via direct inhibition of the APC/C complex Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Cdc20:Phospho-APC/C mediated degradation of Cyclin A APC/C:Cdc20 mediated degradation of mitotic proteins APC-Cdc20 mediated degradation of Nek2A Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Stent thrombosis in response to clopidogrel treatment ( 32472697)	Chronic lymphocytic leukemia ( 28165464 24292274)
Interacting Genes		20 interacting genes: ACTA1 ARHGAP17 BUB1B CDC42 CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAC1 RAPH1 VASP WASF1 WASL WIPF2	26 interacting genes: ANAPC7 AP1B1 AP2B1 AP3B1 AP4B1 APC BRCA2 BUB3 CCNA2 CDC16 CDC20 CDC27 CENPE COMMD4 DNMBP FBXO7 FZR1 HDAC1 KNL1 MAP3K4 PELI1 PLK1 RIPK3 SNCG TP73 TRIP13
Entrez ID		23268	701
HPRD ID		10918	04176
Ensembl ID		ENSG00000107554	ENSG00000156970
Uniprot IDs		A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7	O60566
PDB IDs		1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM	2WVI 3SI5 4GGD 5JJA 5K6S 5KHU 5LCW 5SWF 6TLJ
Enriched GO Terms of Interacting Partners?
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