COPG2 and DRD1

Data Source:
HPRD (in vivo, in vitro)

		COPG2	DRD1
Description		COPI coat complex subunit gamma 2	dopamine receptor D1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol COPI Vesicle Coat Transport Vesicle Growth Cone	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendritic Spine Ciliary Membrane Non-motile Cilium
	Molecular Function	Structural Molecule Activity	Dopamine Neurotransmitter Receptor Activity, Coupled Via Gs G Protein-coupled Receptor Activity Dopamine Neurotransmitter Receptor Activity Protein Binding Dopamine Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Secretion Organelle Transport Along Microtubule	Synaptic Transmission, Dopaminergic G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Dopamine Receptor Signaling Pathway Synapse Assembly Mating Behavior Adult Walking Behavior Visual Learning Positive Regulation Of Gene Expression Transmission Of Nerve Impulse Cerebral Cortex GABAergic Interneuron Migration Positive Regulation Of Cell Migration Vasodilation Dopamine Metabolic Process Response To Drug Positive Regulation Of Potassium Ion Transport Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Synaptic Transmission, Glutamatergic Prepulse Inhibition Phospholipase C-activating Dopamine Receptor Signaling Pathway Cellular Response To Catecholamine Stimulus Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Cellular Response To Dopamine
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Dopamine receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Ziprasidone Cabergoline Cabergoline Olanzapine Olanzapine Methylergometrine Clozapine Phenylpropanolamine Loxapine Loxapine Imipramine Chlorpromazine Chlorpromazine Haloperidol Triflupromazine Amoxapine Lamotrigine Cinnarizine Lisuride Fluphenazine Thioridazine Ergotamine Apomorphine Paroxetine Trimipramine Risperidone Fenoldopam Minaprine Perphenazine Flupentixol Dopamine Dopamine Carphenazine Ergoloid mesylate Pergolide Bromocriptine Quetiapine Levodopa Aripiprazole Chlorprothixene Paliperidone Methotrimeprazine Periciazine Acepromazine Pipotiazine Thioproperazine Thiothixene Zuclopenthixol Iloperidone Rotigotine Lumateperone Mianserin Asenapine Quinagolide Zotepine Pipamperone Dihydro-alpha-ergocryptine Epicriptine Pipradrol Tetrahydropalmatine Dihydrexidine Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Pancreatic cancer ( 25086665) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Cadmium levels ( 26025379) Chin dimples ( 27182965) Falling risk ( 32999390) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Treatment response for severe sepsis ( 22310353) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		12 interacting genes: ARCN1 ARL1 COPB1 COPE COPG1 COPZ1 COPZ2 DRD1 HES4 PTGES3 TAPBP TMED10	16 interacting genes: ADA ADORA1 CALY CAV2 COPG1 COPG2 DNAJC14 DRD3 EPB41L2 FLNA GHSR GRIN1 HRH3 PDCD6IP PRKACA VPS35
Entrez ID		26958	1812
HPRD ID		05074	00538
Ensembl ID		ENSG00000158623	ENSG00000184845
Uniprot IDs		A0A140VK12 Q9NSM7 Q9UBF2	P21728
PDB IDs			1OZ5
Enriched GO Terms of Interacting Partners?
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