COPG2 and TAPBP

Data Source:
HPRD (in vivo)

		COPG2	TAPBP
Description		COPI coat complex subunit gamma 2	TAP binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol COPI Vesicle Coat Transport Vesicle Growth Cone	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane MHC Class I Peptide Loading Complex Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Structural Molecule Activity	Protein Binding ABC-type Peptide Antigen Transporter Activity MHC Class I Protein Binding Peptide Antigen Binding TAP1 Binding TAP2 Binding Unfolded Protein Binding TAP Complex Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Secretion Organelle Transport Along Microtubule	MHC Class Ib Protein Complex Assembly Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Immune Response Regulation Of Gene Expression Peptide Transport Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Peptide Antigen Stabilization Regulation Of Protein Complex Stability Protein-containing Complex Assembly Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	ER-Phagosome pathway Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases			Bare lymphocyte syndrome (BLS) type1
GWAS		Pancreatic cancer ( 25086665) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576 29875488)
Interacting Genes		12 interacting genes: ARCN1 ARL1 COPB1 COPE COPG1 COPZ1 COPZ2 DRD1 HES4 PTGES3 TAPBP TMED10	9 interacting genes: CALR COPB1 COPG1 COPG2 HLA-A HLA-C TAP1 TAP2 UBC
Entrez ID		26958	6892
HPRD ID		05074	09061
Ensembl ID		ENSG00000158623	ENSG00000231925
Uniprot IDs		A0A140VK12 Q9NSM7 Q9UBF2	A0A024RCT1 A0A0A0MSV9 A0A0A0MT98 O15533
PDB IDs			3F8U 6ENY
Enriched GO Terms of Interacting Partners?
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