NUPR1 and KNSTRN

Data Source:
BioGRID (two hybrid)

		NUPR1	KNSTRN
Description		nuclear protein 1, transcriptional regulator	kinetochore localized astrin (SPAG5) binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Protein-DNA Complex Intercellular Bridge Perinuclear Region Of Cytoplasm	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Ruffle Nucleus Cytoplasm Plasma Membrane Centriolar Satellite Microtubule Plus-end Mitotic Spindle
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Acetyltransferase Activator Activity	Protein Binding Protein Homodimerization Activity Microtubule Plus-end Binding
	Biological Process	Acute Inflammatory Response Protein Acetylation Negative Regulation Of Cell Population Proliferation Male Gonad Development Response To Toxic Substance Regulation Of Autophagy Negative Regulation Of Autophagy Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Protein Modification Process Skeletal Muscle Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Negative Regulation Of Glycolytic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation Regulation Of Catalytic Activity Negative Regulation Of Programmed Necrotic Cell Death Protein-containing Complex Assembly Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Autophagosome Assembly Positive Regulation Of Oxidative Phosphorylation Negative Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Type B Pancreatic Cell Proliferation Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Female Gonad Development Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Mitotic Sister Chromatid Segregation Microtubule Cytoskeleton Organization Spindle Organization Chromosome Segregation Cell Migration Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Cellular Response To Epidermal Growth Factor Stimulus
Pathways
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30679032) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Extremely high intelligence ( 29520040) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Inflammatory bowel disease (early onset) ( 19915574) Intelligence (MTAG) ( 29326435) Lamb consumption ( 32066663) Offspring birth weight ( 31043758) Refractive error ( 32231278) Urinary metabolite levels in chronic kidney disease ( 31959995)	Heschl's gyrus morphology ( 25130324) Malaria ( 31844061)
Interacting Genes		16 interacting genes: ABCG8 ALDH1A1 EP300 KNSTRN MAPRE1 MPHOSPH6 MSL1 NPY5R PAXIP1 PTMA RANBP1 RPL41 SEC11A SET STX18 SYNCRIP	17 interacting genes: ABI2 BEX2 CHMP1B CLU HSPB1 IFT20 MAPK6 MAPRE1 MAPRE3 MPHOSPH6 NUPR1 OIP5 PALS2 PPL SGF29 WASHC3 ZDHHC17
Entrez ID		26471	90417
HPRD ID		17814	12669
Ensembl ID		ENSG00000176046	ENSG00000128944
Uniprot IDs		A0A024QZC4 O60356	Q9Y448
PDB IDs
Enriched GO Terms of Interacting Partners?
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