NUPR1 and STX18

Data Source:
BioGRID (two hybrid)

		NUPR1	STX18
Description		nuclear protein 1, transcriptional regulator	syntaxin 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Protein-DNA Complex Intercellular Bridge Perinuclear Region Of Cytoplasm	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane SNARE Complex
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Acetyltransferase Activator Activity	SNAP Receptor Activity Protein Binding Protein Domain Specific Binding
	Biological Process	Acute Inflammatory Response Protein Acetylation Negative Regulation Of Cell Population Proliferation Male Gonad Development Response To Toxic Substance Regulation Of Autophagy Negative Regulation Of Autophagy Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Protein Modification Process Skeletal Muscle Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Negative Regulation Of Glycolytic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation Regulation Of Catalytic Activity Negative Regulation Of Programmed Necrotic Cell Death Protein-containing Complex Assembly Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Autophagosome Assembly Positive Regulation Of Oxidative Phosphorylation Negative Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Type B Pancreatic Cell Proliferation Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Female Gonad Development Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Membrane Fusion Endoplasmic Reticulum Membrane Organization Positive Regulation Of Organelle Assembly Positive Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Golgi Organization
Pathways			COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30679032) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Extremely high intelligence ( 29520040) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Inflammatory bowel disease (early onset) ( 19915574) Intelligence (MTAG) ( 29326435) Lamb consumption ( 32066663) Offspring birth weight ( 31043758) Refractive error ( 32231278) Urinary metabolite levels in chronic kidney disease ( 31959995)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Congenital heart disease ( 23708191)
Interacting Genes		16 interacting genes: ABCG8 ALDH1A1 EP300 KNSTRN MAPRE1 MPHOSPH6 MSL1 NPY5R PAXIP1 PTMA RANBP1 RPL41 SEC11A SET STX18 SYNCRIP	4 interacting genes: BNIP1 DISC1 NSG2 NUPR1
Entrez ID		26471	53407
HPRD ID		17814	06923
Ensembl ID		ENSG00000176046	ENSG00000168818
Uniprot IDs		A0A024QZC4 O60356	Q9P2W9
PDB IDs
Enriched GO Terms of Interacting Partners?
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