WIPI2 and OPTN

  • Data Source:
  • BioGRID (affinity chromatography technology, pull down, proximity labelling technology, affinity chromatography technology)

WIPI2

OPTN

Description WD repeat domain, phosphoinositide interacting 2 optineurin
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bone mineral density x blood lead interaction in current smokers (1df test) ( 29518117)
  • Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117)
  • High light scatter reticulocyte count ( 32888494)
  • Immature fraction of reticulocytes ( 32888494 27863252)
  • Mean corpuscular hemoglobin ( 32888494 27863252)
  • Mean corpuscular hemoglobin concentration ( 32888494)
  • Mean corpuscular volume ( 32888494 27863252)
  • Red blood cell count ( 32888494)
Interacting Genes 16 interacting genes: ARL6IP1 COPS6 DDB1 DGAT2L6 FKBP7 MRRF MTOR OPTN POT1 RABAC1 REEP6 RPTOR STRN4 SYP TERF2IP UBE2L3 69 interacting genes: AIMP1 ARRDC3 ATG16L1 ATG5 CALM1 CCDC13 CDC23 CLTC CMYA5 DAZAP2 DYSF DZIP1 FAM189A2 FLII FOS FTH1 GABARAP GABARAPL1 GABARAPL2 GNAS GRM1 GTF3A HACE1 HSF2BP HSPB1 HTT IRAK1 KANSL1L LITAF LNX2 MAP1LC3A MAP1LC3C MPP1 MYH3 MYO6 PIAS4 PICK1 POU6F2 RAB11A RAB11B RAB12 RAB14 RAB25 RAB8A RBM12 RFFL RNF11 RNF216 SDCBP SLF2 SNX6 TBC1D15 TBC1D17 TNIP1 UBB UBC UQCRQ USP2 VCP WASHC3 WIPI2 ZNF17 ZNF181 ZNF302 ZNF329 ZNF398 ZNF426 ZNF670 ZNF711
Entrez ID 26100 10133
HPRD ID 15679 03891
Ensembl ID ENSG00000157954 ENSG00000123240
Uniprot IDs A0A024R823 Q9Y4P8 Q96CV9
PDB IDs 2LO4 2LUE 3VTV 3VTW 5AAZ 5B83 5EOA 5EOF
Enriched GO Terms of Interacting Partners?
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