WIPI2 and RPTOR

  • Data Source:
  • BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)

WIPI2

RPTOR

Description WD repeat domain, phosphoinositide interacting 2 regulatory associated protein of MTOR complex 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bone mineral density x blood lead interaction in current smokers (1df test) ( 29518117)
  • Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117)
  • High light scatter reticulocyte count ( 32888494)
  • Immature fraction of reticulocytes ( 32888494 27863252)
  • Mean corpuscular hemoglobin ( 32888494 27863252)
  • Mean corpuscular hemoglobin concentration ( 32888494)
  • Mean corpuscular volume ( 32888494 27863252)
  • Red blood cell count ( 32888494)
  • Adult body size ( 32376654)
  • Airway responsiveness in chronic obstructive pulmonary disease ( 25514360)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Bipolar disorder ( 31043756)
  • Body mass index ( 28892062 25673413)
  • Body size at age 10 ( 32376654)
  • Hypertension ( 30487518)
  • Mean arterial pressure ( 30487518)
  • NASH resolution in nonalcoholic steatohepatitis ( 31832568)
  • Nicotine dependence symptom count ( 25555482)
  • Obesity ( 23563607)
  • Pulse pressure ( 29403010 30487518)
  • Systolic blood pressure ( 30487518)
Interacting Genes 16 interacting genes: ARL6IP1 COPS6 DDB1 DGAT2L6 FKBP7 MRRF MTOR OPTN POT1 RABAC1 REEP6 RPTOR STRN4 SYP TERF2IP UBE2L3 23 interacting genes: CILK1 DUXAP9 EIF4EBP1 EIF4EBP2 IRS1 IRS2 LINC00839 MAPK1 MAPK3 MARK4 MLST8 MTOR NRBF2 PLD2 PRKAA1 PRKAA2 RAP1B RHEB RPS6KA1 RPS6KB1 RRAGA RRAGB WIPI2
Entrez ID 26100 57521
HPRD ID 15679 06184
Ensembl ID ENSG00000157954 ENSG00000141564
Uniprot IDs A0A024R823 Q9Y4P8 Q6DKI0 Q8N122
PDB IDs 5H64 6BCU 6BCX 6SB0 6SB2 6U62
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?