GORASP2 and GNGT1

Data Source:
BioGRID (two hybrid)

		GORASP2	GNGT1
Description		golgi reassembly stacking protein 2	G protein subunit gamma transducin 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Membrane	Photoreceptor Inner Segment Heterotrimeric G-protein Complex Plasma Membrane G-protein Beta/gamma-subunit Complex Photoreceptor Disc Membrane
	Molecular Function	Protein Binding	GTPase Activity Protein Binding G-protein Beta-subunit Binding
	Biological Process	Organelle Organization Golgi Organization Spermatogenesis Cell Differentiation Response To Endoplasmic Reticulum Stress Establishment Of Protein Localization To Plasma Membrane Organelle Assembly	Signal Transduction G Protein-coupled Receptor Signaling Pathway Protein Localization Cardiac Muscle Cell Apoptotic Process Rhodopsin Mediated Signaling Pathway Eye Photoreceptor Cell Development Cellular Response To Hypoxia
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization	Activation of G protein gated Potassium channels G-protein activation Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Olfactory Signaling Pathway ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS		Cognitive performance ( 19734545)	Body mass index ( 28552196) Body size at age 10 ( 32376654) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Mosquito bite size ( 28199695) Resting heart rate ( 29769521 27798624) Taxane-induced peripheral neuropathy in breast cancer ( 29278617)
Interacting Genes		143 interacting genes: AAMDC ACY3 ALKBH4 APIP APP ARHGEF15 ARL6IP1 ASMTL ATP6V1G1 ATXN1L BEND5 BLZF1 BTBD3 C1orf94 C21orf91 CARHSP1 CBLB CBY1 CCDC153 CCDC90B CDA CDC23 CDK18 CDKN2D CEP76 CGGBP1 CHMP1A CNTNAP2 CRYAA CRYAA2 CRYAB DCTD DMC1 DNAJB13 DPYSL2 DUSP21 DUSP4 DYRK3 ECHDC1 EIF2B1 EMILIN3 ENOX1 ENOX2 ETHE1 FIG4 GABPB2 GNG7 GNGT1 GOLGA2 GOLGA6L2 GSTZ1 GTF2IRD1 HOXC5 HSBP1 HSPB11 JADE2 KCTD13 KCTD5 KCTD7 KCTD9 KIFC3 KRTAP5-11 LONRF1 LTBP3 MAP1LC3B MAPK1 MAPK14 MAPK8 MATN4 MID2 MIEN1 MIF MORN2 MPLKIP MSC MYOM3 NCOA5 NHSL2 NME1 NMNAT1 NQO2 NUDT5 NUP62 ODC1 PCBD1 PDE9A PNMA5 PRDX3 PRKAB2 PRPS1 PRRC2A PSMA3 PSMD6 RAB1A RAB27B RAB2A RAB39A RAD54B RBM46 REEP6 RGL2 RGS3 RPIA RPS6KA1 SCAND1 SELENBP1 SEPTIN1 SEPTIN14 SHMT1 STOX1 TAGLN TCF4 TEKT3 TGFA TLE5 TMED10 TMED2 TMED3 TP53RK TPH1 TRAF1 TRAF2 TRAF4 TRAF5 TRAPPC6A TRIM38 TRPT1 TSC22D1 TSC22D4 TSEN15 TSN TTC19 TXLNA UBE2Z UBL3 VPS37B VPS52 XPNPEP1 ZBED1 ZBTB14 ZMAT1 ZMYND19 ZNF148	14 interacting genes: GNAS GNB1 GNB2 GNB4 GNB5 GORASP2 IKBKG MSANTD4 NAGA PDCL PLEKHB1 RHO UBXN4 ZNF277
Entrez ID		26003	2792
HPRD ID		08303	01805
Ensembl ID		ENSG00000115806	ENSG00000127928
Uniprot IDs		Q9H8Y8	P63211
PDB IDs		3RLE 4EDJ
Enriched GO Terms of Interacting Partners?
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