FTL and PALS2

Data Source:
HPRD (two hybrid)

		FTL	PALS2
Description		ferritin light chain	protein associated with LIN7 2, MAGUK family member
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Intracellular Ferritin Complex Membrane Azurophil Granule Lumen Autolysosome Extracellular Exosome	Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Iron Ion Binding Protein Binding Ferrous Iron Binding Ferric Iron Binding Identical Protein Binding	Protein Binding
	Biological Process	Iron Ion Transport Cellular Iron Ion Homeostasis Intracellular Sequestering Of Iron Ion Neutrophil Degranulation Iron Ion Homeostasis	Protein-containing Complex Assembly
Pathways		Scavenging by Class A Receptors Golgi Associated Vesicle Biogenesis Neutrophil degranulation Iron uptake and transport
Drugs		Iron Dextran Protoporphyrin Ferric pyrophosphate Sodium ferric gluconate complex Ferric pyrophosphate citrate
Diseases		Neurodegeneration with brain iron accumulation (NBIA); Hallervorden-Spatz syndrome; Neuroferritinopathy; Aceruloplasminemia
GWAS
Interacting Genes		29 interacting genes: CLEC4G FTH1 GADD45A GLP1R GRB2 HTT IGDCC3 KNG1 KPNA3 MAP3K12 MEOX2 MPHOSPH6 MTNR1B MYOC MYOG NTAQ1 PALS2 PIK3CA PPP1CC PTN RAP2A SDCBP SLC13A1 SMAD9 SPINK7 TAF10 USHBP1 VKORC1 ZDHHC17	30 interacting genes: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A LIN7B LIN7C MT2P1 MTREX NDN NFKB1 PARN RPS20 SMARCA4 SNX9 THOP1
Entrez ID		2512	51678
HPRD ID		00616	09509
Ensembl ID		ENSG00000087086	ENSG00000105926
Uniprot IDs		A0A384MDR3 P02792	A0A024RA25 B8ZZG1 Q9NZW5
PDB IDs		2FFX 2FG4 2FG8 3KXU 4V6B 5LG8 6TR9 6TS0 6TS1 6TSA 6TSF 6TSJ 6WX6
Enriched GO Terms of Interacting Partners?
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