CADM1 and DNAJC5

Data Source:
BioGRID (fluorescent resonance energy transfer)

		CADM1	DNAJC5
Description		cell adhesion molecule 1	DnaJ heat shock protein family (Hsp40) member C5
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GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Integral Component Of Membrane Basolateral Plasma Membrane Synapse	Mitochondrion Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Membrane Anchored Component Of Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Chromaffin Granule Membrane Intracellular Membrane-bounded Organelle Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding PDZ Domain Binding Protein Homodimerization Activity	Protein Binding ATP-dependent Protein Binding
	Biological Process	Positive Regulation Of Cytokine Production T Cell Mediated Cytotoxicity Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Multicellular Organism Development Spermatogenesis Cell Recognition Viral Process Cell Differentiation Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Activated T Cell Proliferation Detection Of Stimulus	Exocytosis Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neutrophil Degranulation Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle
Pathways		Adherens junctions interactions Nectin/Necl trans heterodimerization	Neutrophil degranulation GABA synthesis, release, reuptake and degradation
Drugs
Diseases		Nasopharyngeal cancer
GWAS		Adult body size ( 32376654) Anorexia nervosa ( 31308545) Body mass index ( 28552196 31978080 28892062 25673413) Body size at age 10 ( 32376654) Cardiovascular risk factors (age interaction) ( 20838585) Childhood body mass index ( 33045005) Chronotype ( 30696823) Coffee consumption ( 31046077) Cutaneous squamous cell carcinoma ( 27424798 32041948) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Heel bone mineral density ( 30598549 28869591) Left-handedness ( 32989287) Menarche (age at onset) ( 27182965 25231870) Obesity-related traits ( 23251661) Serum linoleic acid concentration in metabolic syndrome ( 31991592) Thyroid stimulating hormone levels ( 30367059 32769997) Type 2 diabetes (age of onset) ( 28060188) Waist circumference ( 28552196)	Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate cancer ( 23535732)
Interacting Genes		7 interacting genes: ATF7IP CASK DNAJC5 EPB41L3 MPP3 PSMA6 SDCBP	56 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CASK CD2 CFTR CGB5 CLCN3 EFNB1 ERC1 FAS FCHO1 GRM8 HBA2 HGS KHDC4 LIN7A LIN7C NECAP1 NRXN3 NUMB PPFIA1 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP1 SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 STX7 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7
Entrez ID		23705	80331
HPRD ID		05746	08539
Ensembl ID		ENSG00000182985	ENSG00000101152
Uniprot IDs		A0A4Z1 Q9BY67 X5D7A8 X5D8W0 X5DQR8 X5DQS5	Q6AHX3 Q9H3Z4
PDB IDs		3BIN 4H5S	2N04 2N05
Enriched GO Terms of Interacting Partners?
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