DNAJC5 and SV2A

Data Source:
BioGRID (fluorescent resonance energy transfer)

		DNAJC5	SV2A
Description		DnaJ heat shock protein family (Hsp40) member C5	synaptic vesicle glycoprotein 2A
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GO Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Membrane Anchored Component Of Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Chromaffin Granule Membrane Intracellular Membrane-bounded Organelle Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane	Endoplasmic Reticulum Plasma Membrane Cell-cell Junction Synaptic Vesicle Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane Dendrite Synaptic Vesicle Membrane Neuromuscular Junction Neuron Projection Neuronal Cell Body Presynaptic Active Zone Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Protein Binding ATP-dependent Protein Binding	Protein Kinase Binding Transmembrane Transporter Activity
	Biological Process	Exocytosis Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neutrophil Degranulation Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle	Cellular Calcium Ion Homeostasis Regulation Of Gamma-aminobutyric Acid Secretion Synaptic Vesicle Priming Transmembrane Transport
Pathways		Neutrophil degranulation GABA synthesis, release, reuptake and degradation	Toxicity of botulinum toxin type D (botD) Toxicity of botulinum toxin type A (botA) Toxicity of botulinum toxin type F (botF) Toxicity of botulinum toxin type E (botE)
Drugs			Levetiracetam Brivaracetam Seletracetam
Diseases
GWAS		Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate cancer ( 23535732)	Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Height ( 25429064 31562340 18391951) Lung function (FEV1) ( 26635082)
Interacting Genes		56 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CASK CD2 CFTR CGB5 CLCN3 EFNB1 ERC1 FAS FCHO1 GRM8 HBA2 HGS KHDC4 LIN7A LIN7C NECAP1 NRXN3 NUMB PPFIA1 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP1 SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 STX7 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7	4 interacting genes: ATXN1 DNAJC5 LAMA5 LTB4R2
Entrez ID		80331	9900
HPRD ID		08539	08922
Ensembl ID		ENSG00000101152	ENSG00000159164
Uniprot IDs		Q6AHX3 Q9H3Z4	B4E000 Q7L0J3
PDB IDs		2N04 2N05	4V11
Enriched GO Terms of Interacting Partners?
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