CADM1 and EPB41L3

Data Source:
HPRD (in vivo, in vitro)

		CADM1	EPB41L3
Description		cell adhesion molecule 1	erythrocyte membrane protein band 4.1 like 3
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GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Integral Component Of Membrane Basolateral Plasma Membrane Synapse	Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Cell Junction Axolemma Paranode Region Of Axon Juxtaparanode Region Of Axon
	Molecular Function	Signaling Receptor Binding Protein Binding PDZ Domain Binding Protein Homodimerization Activity	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein-membrane Anchor Activity
	Biological Process	Positive Regulation Of Cytokine Production T Cell Mediated Cytotoxicity Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Multicellular Organism Development Spermatogenesis Cell Recognition Viral Process Cell Differentiation Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Activated T Cell Proliferation Detection Of Stimulus	Regulation Of Cell Growth Protein Localization To Paranode Region Of Axon Apoptotic Process Biological_process Regulation Of Cell Shape Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Paranodal Junction Assembly Actomyosin Structure Organization Myelin Maintenance Neuron Projection Morphogenesis Protein Localization To Juxtaparanode Region Of Axon Protein Localization To Plasma Membrane
Pathways		Adherens junctions interactions Nectin/Necl trans heterodimerization	Neurexins and neuroligins
Drugs
Diseases		Nasopharyngeal cancer
GWAS		Adult body size ( 32376654) Anorexia nervosa ( 31308545) Body mass index ( 28552196 31978080 28892062 25673413) Body size at age 10 ( 32376654) Cardiovascular risk factors (age interaction) ( 20838585) Childhood body mass index ( 33045005) Chronotype ( 30696823) Coffee consumption ( 31046077) Cutaneous squamous cell carcinoma ( 27424798 32041948) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Heel bone mineral density ( 30598549 28869591) Left-handedness ( 32989287) Menarche (age at onset) ( 27182965 25231870) Obesity-related traits ( 23251661) Serum linoleic acid concentration in metabolic syndrome ( 31991592) Thyroid stimulating hormone levels ( 30367059 32769997) Type 2 diabetes (age of onset) ( 28060188) Waist circumference ( 28552196)	Cerebral amyloid deposition (PET imaging) ( 26252872) Chronic kidney disease ( 31152163) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Glomerular filtration rate (creatinine) ( 28452372) Optic nerve head parameters (multi-trait analysis) ( 31798171) Sleep duration ( 25469926) Social communication problems ( 24564958) Thyroid nodules ( 30099483) Vertical cup-disc ratio ( 31798171)
Interacting Genes		7 interacting genes: ATF7IP CASK DNAJC5 EPB41L3 MPP3 PSMA6 SDCBP	19 interacting genes: ATXN1L CADM1 CEP152 CLNS1A CNTNAP2 HSPB1 IGSF21 MBIP PAXIP1 PSEN1 SPANXN2 SPTBN1 TCF4 UNC13A YWHAB YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		23705	23136
HPRD ID		05746	05622
Ensembl ID		ENSG00000182985	ENSG00000082397
Uniprot IDs		A0A4Z1 Q9BY67 X5D7A8 X5D8W0 X5DQR8 X5DQS5	A0A0A0MRA8 A8K968 Q9Y2J2
PDB IDs		3BIN 4H5S	2HE7 3BIN 6IBE
Enriched GO Terms of Interacting Partners?
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