FOSB and DNMT3L

Data Source:
BioGRID (pull down)

		FOSB	DNMT3L
Description		FosB proto-oncogene, AP-1 transcription factor subunit	DNA methyltransferase 3 like
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Nucleus Cytosol ESC/E(Z) Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Enzyme Activator Activity Enzyme Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Female Pregnancy Response To Mechanical Stimulus Response To Progesterone Cellular Response To Hormone Stimulus Response To Drug Response To Morphine Positive Regulation Of Transcription By RNA Polymerase II Response To Corticosterone Response To CAMP Cellular Response To Calcium Ion	DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Male Meiosis I Spermatogenesis DNA Methylation On Cytosine DNA Methylation Involved In Gamete Generation Negative Regulation Of Transcription, DNA-templated Stem Cell Differentiation Regulation Of Catalytic Activity Negative Regulation Of DNA Methylation Positive Regulation Of DNA Methylation
Pathways		Estrogen-dependent gene expression NGF-stimulated transcription NGF-stimulated transcription	DNA methylation
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Heel bone mineral density ( 30598549 28869591)
Interacting Genes		28 interacting genes: AGXT ATF2 CENPO CREB5 CYTH4 DNMT3L ENKD1 EP300 FAM222B FAM90A1 FOXP3 GLIS2 JUN JUNB JUND NCK2 NEDD9 PHC2 PHF1 POGZ POU6F2 ROR2 SRA1 TENT5B TLE5 TLX3 VEZF1 ZC3H10	78 interacting genes: - ASH2L ATF1 ATF2 ATF3 ATF4 BLZF1 CDX2 CREB1 CREBL2 CREM DDIT3 DLX4 DMTF1 DNMT3A DNMT3B DR1 E2F3 E2F5 E2F6 EGR1 EGR2 EGR4 ESR1 ESR2 ETS1 F2RL1 FOS FOSB FOSL1 FOSL2 GATA1 GMEB1 GSK3B GTF2H2 GTF2I GTF3C5 H2AC20 H2BC21 H3C14 H4C14 HAND1 HAND2 HDAC1 HNF4G HOXA5 HOXC11 ID1 JUN JUNB KLF12 LDB1 LHX2 MAFK MECP2 MED7 MEF2A MEF2D NFIL3 NFKB1 NR1H2 NR1I2 NR1I3 NR2E1 NR3C1 NR6A1 NUDT21 PDZD4 PHPT1 RELA RSL24D1 RXRA SMAD1 SMAD3 SMAD4 TLE5 TP53 YY1
Entrez ID		2354	29947
HPRD ID		01270	09417
Ensembl ID		ENSG00000125740	ENSG00000142182
Uniprot IDs		A0A024R0P6 K7EKC1 P53539	Q9UJW3
PDB IDs		5VPA 5VPB 5VPC 5VPD 5VPE 5VPF 6UCI 6UCL 6UCM	2PV0 2PVC 2QRV 4U7P 4U7T 5YX2 6BRR 6F57 6KDA 6KDB 6KDL 6KDP 6KDT 6U8P 6U8V 6U8W 6U8X 6U90 6U91 6W89 6W8B 6W8D 6W8J
Enriched GO Terms of Interacting Partners?
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