SIRT1 and CHFR

  • Data Source:
  • BioGRID (enzymatic study)

SIRT1

CHFR

Description sirtuin 1 checkpoint with forkhead and ring finger domains
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cognitive function ( 24684796)
  • Height ( 31562340)
  • Mean corpuscular hemoglobin ( 32888494)
  • Mean corpuscular volume ( 32888494)
  • Refractive error ( 32231278)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Systolic blood pressure x quantitative lifestyle risk score interaction (1df test) ( 32227373)
  • Systolic blood pressure x quantitative lifestyle risk score interaction (2df test) ( 32227373)
Interacting Genes 63 interacting genes: AFP AKT1 AR ARNTL BCL11A BHLHE41 BRIP1 CDK6 CENATAC CHFR CLOCK CSNK2B CTTN E2F1 EP300 ESRRA EZH2 FOS FOXM1 FOXO1 FOXO3 GAPDH H1-5 H3C1 HES1 HEY2 HIC1 HIPK2 HNF4A HOXB9 MAPK8 MAPT MPHOSPH8 MYCN NBN NDN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARG PPARGC1A PRMT1 PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SNW1 STK11 STK4 SUMO2 TP53 TP73 TRIM28 UBE2I VDR 30 interacting genes: AURKA BRD4 CBLC EEF1G GABBR1 GRB10 GRB14 HDAC1 HDAC2 ITGAE PML RNF125 RNF7 SIRT1 SMARCA4 SMARCB1 SMARCD1 TRIM9 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2L1 UBE2N UBE2W WDR47
Entrez ID 23411 55743
HPRD ID 08381 05552
Ensembl ID ENSG00000096717 ENSG00000072609
Uniprot IDs A0A024QZQ1 A8K128 B0QZ35 E9PC49 Q96EB6 Q96EP1
PDB IDs 4I5I 4IF6 4IG9 4KXQ 4ZZH 4ZZI 4ZZJ 5BTR 1LGP 1LGQ 2XOC 2XOY 2XOZ 2XP0
Enriched GO Terms of Interacting Partners?
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