SASH1 and SPG7

  • Data Source:
  • BioGRID (two hybrid)

SASH1

SPG7

Description SAM and SH3 domain containing 1 SPG7 matrix AAA peptidase subunit, paraplegin
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 20061627)
  • Chronotype ( 30696823)
  • Gait speed in old age ( 28077804)
  • Hypothyroidism ( 27182965)
  • Idiopathic dilated cardiomyopathy ( 29495422)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Pneumococcal meningitis x streptococcus pneumoniae antigen allele interaction ( 31092817)
  • Protein quantitative trait loci ( 18464913)
  • Resting-state electroencephalogram vigilance ( 29703947)
  • Rotator cuff tears ( 26350878)
  • Thyroid hormone levels ( 23408906)
  • Thyroid stimulating hormone levels ( 32769997)
  • Type 2 diabetes nephropathy ( 21150874)
  • Hair morphology traits ( 30166351)
  • Heel bone mineral density ( 30598549)
  • Type 2 diabetes ( 30297969)
  • White coat effect (clinic systolic blood pressure minus ambulatory systolic blood pressure) ( 31044621)
Interacting Genes 26 interacting genes: AFF1 AKAP10 ARRB1 ASCC2 C1D CCNDBP1 CNKSR1 CRK CRKL CTNNA1 EPS8L2 EXOC8 IKBKB JADE2 JADE3 KHDRBS1 KIF3B PPP4R1 RBM12B SECISBP2L SKIL SNX1 SPG7 SYNE2 TNKS2 UTRN 29 interacting genes: BDKRB2 CCNDBP1 CYSRT1 HNRNPK HSF2BP KHDRBS2 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP4-12 KRTAP5-9 LRIF1 LZTS2 MAPK6 MDFI MTUS2 NBPF19 NOTCH2NLA PLSCR1 PNMA1 PSME3 PSTPIP1 RALY RBPMS SASH1 SPATS1 STAMBP TRIM28
Entrez ID 23328 6687
HPRD ID 06408 04149
Ensembl ID ENSG00000111961 ENSG00000197912
Uniprot IDs O94885 A0A2R8Y632 Q9UQ90
PDB IDs 2DL0 2EBP 2QZ4
Enriched GO Terms of Interacting Partners?
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