SASH1 and SYNE2

  • Data Source:
  • BioGRID (two hybrid)

SASH1

SYNE2

Description SAM and SH3 domain containing 1 spectrin repeat containing nuclear envelope protein 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 20061627)
  • Chronotype ( 30696823)
  • Gait speed in old age ( 28077804)
  • Hypothyroidism ( 27182965)
  • Idiopathic dilated cardiomyopathy ( 29495422)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Pneumococcal meningitis x streptococcus pneumoniae antigen allele interaction ( 31092817)
  • Protein quantitative trait loci ( 18464913)
  • Resting-state electroencephalogram vigilance ( 29703947)
  • Rotator cuff tears ( 26350878)
  • Thyroid hormone levels ( 23408906)
  • Thyroid stimulating hormone levels ( 32769997)
  • Type 2 diabetes nephropathy ( 21150874)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Atrial fibrillation ( 28416818 30061737 29892015 22544366)
  • Blond vs. brown/black hair color ( 30531825)
  • Cutaneous malignant melanoma ( 32341527)
  • Cutaneous melanoma or hair colour ( 32341527)
  • Depression ( 29700475)
  • HDL cholesterol levels ( 32109663)
  • Metabolite levels ( 23823483)
  • Nevus count or cutaneous melanoma ( 32341527 30429480)
  • PR interval ( 32439900)
  • Psoriasis ( 25854761)
  • Pulmonary function decline ( 22424883)
  • Serum metabolite concentrations in chronic kidney disease ( 29545352)
  • Serum metabolite ratios in chronic kidney disease ( 29545352)
  • Sphingomyelin levels ( 31551469)
  • Youthful appearance (self-reported) ( 32339537)
Interacting Genes 26 interacting genes: AFF1 AKAP10 ARRB1 ASCC2 C1D CCNDBP1 CNKSR1 CRK CRKL CTNNA1 EPS8L2 EXOC8 IKBKB JADE2 JADE3 KHDRBS1 KIF3B PPP4R1 RBM12B SECISBP2L SKIL SNX1 SPG7 SYNE2 TNKS2 UTRN 11 interacting genes: ABI1 ACTC1 BRAP CALM1 MAPK3 MAPK8IP2 MEOX2 MTNR1B PML SASH1 UBC
Entrez ID 23328 23224
HPRD ID 06408 09763
Ensembl ID ENSG00000111961 ENSG00000054654
Uniprot IDs O94885 Q6MZP0 Q8WXH0
PDB IDs 2DL0 2EBP 4DXS 4FI9
Enriched GO Terms of Interacting Partners?
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