FMO3 and CLEC10A

Data Source:
BioGRID (two hybrid)

		FMO3	CLEC10A
Description		flavin containing dimethylaniline monoxygenase 3	C-type lectin domain containing 10A
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Monooxygenase Activity N,N-dimethylaniline Monooxygenase Activity Protein Binding Trimethylamine Monooxygenase Activity Flavin Adenine Dinucleotide Binding NADP Binding	Protein Binding Carbohydrate Binding
	Biological Process	Xenobiotic Metabolic Process	Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Endocytosis Innate Immune Response
Pathways		FMO oxidises nucleophiles Defective FMO3 causes Trimethylaminuria (TMAU)	Dectin-2 family
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Lentiform nucleus volume ( 22903471)	Carotid intima media thickness x smoking interaction ( 32117412) GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		4 interacting genes: CLEC10A CREB3 SACM1L SGSM3	24 interacting genes: ACSF2 ADIPOQ APOD BET1 C3orf52 CLN6 FMO3 FXYD6 GIMAP1 MALL NAPB PEX16 PRAF2 SEC22A SLC38A7 SMCO4 TMEM218 TNF TRARG1 TSPO UNC50 VSTM1 ZDHHC15 ZFPL1
Entrez ID		2328	10462
HPRD ID		00633	12076
Ensembl ID		ENSG00000007933	ENSG00000132514
Uniprot IDs		A0A024R8Z4 B7Z3M2 B7Z543 P31513 Q53FW5	J3KR22 Q8IUN9
PDB IDs			6PUV 6PY1
Enriched GO Terms of Interacting Partners?
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